In vivo testing ESR 4.1
In vitro testing of novel aminoglycosides antibiotics, and resistance mechanism of Bdellovibrio bacteriovorus
Once new lead compounds and antimicrobials have been developed through discovery and synthetic approaches, an initial selection process will be performed followed by extensive antimicrobial testing in vitro and ex vivo. The most promising antimicrobial drug candidates will thereafter also be tested in appropriate animal models. To this end, the research of ESR 4.1 will build on one of the largest strain collections of MDR bacteria in Europe, which is available within the Department of Medical Microbiology at the University Medical Center Groningen (UMCG).
Department: Medical Microbiology, UMCG, GSMS
Principal investigator(s): Alexander Friedrich, Jan Maarten van Dijl